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Virion Structure and Genomic Organization. HRVs members of the family Picornaviridae and the genus Enterovirus are positive-sense single-stranded-RNA (ssRNA) viruses of approximately 7200 bp.The viral genome consists of a single gene whose translated protein is cleaved by virally encoded proteases to produce 11 proteins (Fig. 1).Four proteins VP1 VP2 VP3 and VP4 …
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